Salmonella enterica pathogenisity islands (PAI)

PAI Function Insertion Site GenBank Accession 
centisome 63 Iron uptake system, sit operon fhlA AF128999 
CS54 island Intestinal colonization and persistence determinants (shdA, ratA, ratB, sivI, sivH) xseA/yfgK AF140550 
HPI P4-like integrase; located within a high-pathogenicity-island (HPI) region FJ212116 
FJ212115 
Not named putative pathogenicity island protein (ssaD) gene JQ071613 
SESS LEE Type VI secretion system effector tRNA-pheV JQ747523
JQ747540
SGI1 Multi drug resistance (ApCmFlSmSpTc) FJ477835 
Multi drug resistance (ampicillin, gentamicin, streptomycin, spectinomycin, sulfathiazole, tetracycline, and nalidixic acid) thdF/yidY AY463797 
SGI2 Multi drug resistance (trimethoprim, sulfonamides, chloramphenicol, and tetracycline) AY963803 
SPI-1 invA; nonfunctional invasion protein A due to mutation; located on the Salmonella pathogenicity island 1 JN982040 
JN982041 
SPI-1 Type III secretion system, invasion into epithelial cells, apoptosis (InvA, OrgA, SptP, SipA, SipB, SipC, SipD, SopE, prgH) Not published AY956822 
AY956824 
AY956825 
AY956823 
fhlA/mutS AF148689 
NC_006905_P5
NC_003198_P5
NC_004631_P2
SPI-10 Fibrin-like protein (sefD) Not published AY956839 
Phage 46 and the sefA-R chaperone-usher fimbrial operon tRNA-leu NC_003198_P10
SPI-11 sopB, mppA, icdA, envF, msgA, envE, pagD, pagC Gifsy-1 prophage NC_006905_P2
SPI-12 msgA, narP tRNA-pro NC_006905_P4
SPI-13 LysR family transcriptional regulation (gtrB) tRNA-pheV AY956834 
Acetyl-coA dehydrolase (gacD) AY956832 
Trancriptional regulation (gtrA) AY956833 
SPI-14 Electron transfer favoprotein beta subunit (gpiA) Not published AY956835 
Trancriptional regulation (gpiB) AY956836 
SPI-2 spiC; pathogenicity island 2 secreted effector protein JN673271 
JN673273 
Type III secretion system, required for systemic infection and intracellular pathogenesis by facilitating replication of intracellular bacteria within membrane-bound Salmonella-containing vacuoles (SsaJ, SseABC, SpiC) tRNA-valV AJ224892 
spiC; pathogenicity island 2 secreted effector protein JN673268 
JN673270 
Type III secretion system, required for systemic infection and intracellular pathogenesis by facilitating replication of intracellular bacteria within membrane-bound Salmonella-containing vacuoles tRNA-valV AY956826 
AY956827 
AY956828 
AY956830 
AY956829 
AF020808 
spiC; pathogenicity island 2 secreted effector protein JN673269 
JN673272 
Type III secretion system, required for systemic infection and intracellular pathogenesis by facilitating replication of intracellular bacteria within membrane-bound Salmonella-containing vacuoles tRNA-val NC_006905_P3
NC_003198_P3
NC_004631_P1
SPI-3 Invasion, survival in monocytes, Mg2+ uptake (MgtC, B, MarT, MisL) tRNA selC AF106566
AY144489 
Invasion, survival in monocytes, Mg2+ uptake (sugR, rhuMMgtC, B, MarT, MisL), putative fimbrial-like protein(yadC/K./L/M), probable pilin chaperone(ecpD1/D2) AY144490 
Invasion, survival in monocytes, Mg2+ uptake (MgtC, B, MarT, MisL) NC_006905_P6
tRNA-pro NC_003198_P7
SPI-4 Type I secretion system, putative toxin secretion, apoptosis, required for intracellular survival in macrophages ssb/soxSR AF060869
Type I secretion system, putative toxin secretion, apoptosis, required for intracellular survival in macrophages; large secretion protein(siiE) and Type I secretion system components(siiC,D,F) Not published AJ576316
Type I secretion system, putative toxin secretion, apoptosis, required for intracellular survival in macrophages, genes weakly similar to RTX-like toxins ssb/soxSR NC_006905_P7
ssb NC_003198_P8
SPI-5 Invasion, survival in monocytes, Mg2+ uptake (rhuM, MgtC, B, MarT, MisL) tRNA-selC AY144491 
Effector proteins for SPI-1 and SPI-2 (SopB, SigD, PipB) tRNA-serT AF060858 
Invasion, survival in monocytes, Mg2+ uptake (MgtC, B, MarT, MisL) tRNA-selC AY144492 
sopB Not published AF323078 
AF323077 
Effector proteins for SPI-1 and SPI-2 (SopB, SigD, PipB) tRNA-ser NC_006905_P1
NC_003198_P2
SPI-6 Altered metabolic requirements, 4-hydroxybutyrate coA transferase (cat2) tRNA-pheV AF376036 
tRNA-asp NC_003198_P1
SPI-7 Vi exopolysaccharide, SopE prophage and a type IVB pilus operon tRNA-phe NC_003198_P9
NC_004631_P3
tRNA-pheU AF000001 
SPI-8 Two bacteriocin pseudogenes, genes conferring immunity to the bacteriocins tRNA-phe NC_003198_P6
SPI-9 Type I secretory apparatus, large RTX-like protein NC_003198_P4

Adapted from: 

PAIDB v2.0

http://www.paidb.re.kr/browse_pais.php?m=p#Salmonella%20enterica

Leave a Reply